Palmitoyl Tetrapeptide-72 Amide
A lipidated peptide. The maker links it to skin firmness support; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. Well tolerated; data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Palmitoyl Tetrapeptide-72 Amide is a short synthetic peptide attached to a palmitic acid residue. The fatty part helps the molecule pass through the stratum corneum, while the peptide fragment acts as a biomimetic signal in anti-aging formulas and firming serums. On efficacy, an honest read. The peptide has a biologically plausible basis, but most data come from the manufacturer rather than large independent studies. It is reasonable to treat it as a supporting component within a complete formula, not as an active that reshapes skin on its own. No miracle claims. Applied topically, the molecule barely reaches systemic circulation, so use during pregnancy and breastfeeding is considered fine. There are no warning signals for these stages. Tolerance is good: low irritation potential and low allergy risk. It suits sensitive skin. As with any new ingredient, if your skin reacts easily, introduce it gradually.
Frequently asked questions
Is Palmitoyl Tetrapeptide-72 Amide safe during pregnancy?
Palmitoyl Tetrapeptide-72 Amide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Palmitoyl Tetrapeptide-72 Amide for?
Palmitoyl Tetrapeptide-72 Amide suits: normal, dry, combination, oily, sensitive.
What is Palmitoyl Tetrapeptide-72 Amide and what does it do in cosmetics?
A lipidated peptide.
What's the INCI name for Palmitoyl Tetrapeptide-72 Amide?
The INCI name is Palmitoyl Tetrapeptide-72 Amide.
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