A lipidated peptide. The maker links it to skin firmness support; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. Well tolerated; data limited.
Palmitoyl Tetrapeptide-72 Amide is a short synthetic peptide attached to a palmitic acid residue. The fatty part helps the molecule pass through the stratum corneum, while the peptide fragment acts as a biomimetic signal in anti-aging formulas and firming serums. On efficacy, an honest read. The peptide has a biologically plausible basis, but most data come from the manufacturer rather than large independent studies. It is reasonable to treat it as a supporting component within a complete formula, not as an active that reshapes skin on its own. No miracle claims. Applied topically, the molecule barely reaches systemic circulation, so use during pregnancy and breastfeeding is considered fine. There are no warning signals for these stages. Tolerance is good: low irritation potential and low allergy risk. It suits sensitive skin. As with any new ingredient, if your skin reacts easily, introduce it gradually.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Palmitoyl Tetrapeptide-72 Amide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Palmitoyl Tetrapeptide-72 Amide suits: normal, dry, combination, oily, sensitive.
A lipidated peptide.
The INCI name is Palmitoyl Tetrapeptide-72 Amide. It may also appear as: Пальмитоил тетрапептид-72 амид.
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