Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
A synthetic lipopeptide. The maker links it to skin firmness and wrinkle smoothing; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. The maker links it to skin firmness; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate is a synthetic peptide linked to palmitic acid for better penetration. INCI: Palmitoyl Dipeptide-5 Diaminohydroxybutyrate. In a formula it works as a signal peptide with a claimed firming and anti-aging action: it is linked to support of collagen synthesis and skin firmness. Signal peptides are a promising class, but the evidence base for specific molecules is mostly from manufacturer studies, and the effect is mild and needs time. It is a supporting active rather than a potent treatment. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.
Frequently asked questions
Is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate safe during pregnancy?
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate for?
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate suits: normal, dry, combination, oily, sensitive.
What is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate and what does it do in cosmetics?
A synthetic lipopeptide.
What's the INCI name for Palmitoyl Dipeptide-5 Diaminohydroxybutyrate?
The INCI name is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate. It may also appear as: Palmitoyl Dipeptide-5.
See Palmitoyl Dipeptide-5 Diaminohydroxybutyrate in a product composition right on the store page
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