A synthetic lipopeptide. The maker links it to skin firmness and wrinkle smoothing; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. The maker links it to skin firmness; independent data limited.
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate is a synthetic peptide linked to palmitic acid for better penetration. INCI: Palmitoyl Dipeptide-5 Diaminohydroxybutyrate. In a formula it works as a signal peptide with a claimed firming and anti-aging action: it is linked to support of collagen synthesis and skin firmness. Signal peptides are a promising class, but the evidence base for specific molecules is mostly from manufacturer studies, and the effect is mild and needs time. It is a supporting active rather than a potent treatment. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate suits: normal, dry, combination, oily, sensitive.
A synthetic lipopeptide.
The INCI name is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate. It may also appear as: Пальмитоил дипептид-5 диаминогидроксибутират, Palmitoyl Dipeptide-5.
Published: · updated: