Palmitoyl Grape Seed Extract
An active in the grape-based Caudalie range. The maker links it to antioxidant protection; independent data are limited. Well tolerated.
Evidence by route
Topical application
A grape active. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Palmitoyl Grape Seed Extract is a grape-seed extract linked to palmitic acid for better solubility in the oil phase. INCI: Palmitoyl Grape Seed Extract. In a formula it works as an antioxidant: grape seeds are rich in polyphenols (proanthocyanidins) that neutralize free radicals and support defense against oxidative stress. Of all grape-derived components, seed extract is the richest in active substances, so the antioxidant rationale here is stronger than for grape water or juice. That said, it is a supporting active rather than a treatment with a large clinical base. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.
Frequently asked questions
Is Palmitoyl Grape Seed Extract safe during pregnancy?
Palmitoyl Grape Seed Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Palmitoyl Grape Seed Extract for?
Palmitoyl Grape Seed Extract suits: normal, dry, combination, oily, sensitive.
What is Palmitoyl Grape Seed Extract and what does it do in cosmetics?
An active in the grape-based Caudalie range.
What's the INCI name for Palmitoyl Grape Seed Extract?
The INCI name is Palmitoyl Grape Seed Extract.
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