Hydroxypropyl Tetrahydropyrantriol
An anti-aging active (Pro-Xylane). It supports skin density and holds moisture, common in anti-wrinkle formulas. Well tolerated.
Evidence by route
Topical application
A functional anti-aging active. Safe, well tolerated.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Hydroxypropyl tetrahydropyrantriol (INCI Hydroxypropyl Tetrahydropyrantriol), known as pro-xylane, is an anti-aging active of synthetic origin inspired by plant sugars. In a formula it aims to support skin density and hold water, and it is common in creams and serums of anti-wrinkle lines. Here is an active with some track record. It has manufacturer studies pointing to improvements in firmness and skin quality, though independent evidence is more limited than for reference actives such as retinoids or vitamin C. Treat it as a solid supporting anti-aging ingredient, not as a replacement for those actives. Systemic exposure from topical use is negligible, so it can be used in pregnancy and breastfeeding. Tolerance is very good: irritation and allergy risk are low, suitable even for sensitive skin. It does not dry the skin and is not linked to pore clogging, so it fits well into maintenance routines.
Frequently asked questions
Is Hydroxypropyl Tetrahydropyrantriol safe during pregnancy?
Hydroxypropyl Tetrahydropyrantriol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Hydroxypropyl Tetrahydropyrantriol for?
Hydroxypropyl Tetrahydropyrantriol suits: normal, dry, combination, oily, sensitive.
What is Hydroxypropyl Tetrahydropyrantriol and what does it do in cosmetics?
An anti-aging active (Pro-Xylane).
What's the INCI name for Hydroxypropyl Tetrahydropyrantriol?
The INCI name is Hydroxypropyl Tetrahydropyrantriol. It may also appear as: Pro-Xylane.
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