An anti-aging active (Pro-Xylane). It supports skin density and holds moisture, common in anti-wrinkle formulas. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A functional anti-aging active. Safe, well tolerated.
Hydroxypropyl tetrahydropyrantriol (INCI Hydroxypropyl Tetrahydropyrantriol), known as pro-xylane, is an anti-aging active of synthetic origin inspired by plant sugars. In a formula it aims to support skin density and hold water, and it is common in creams and serums of anti-wrinkle lines. Here is an active with some track record. It has manufacturer studies pointing to improvements in firmness and skin quality, though independent evidence is more limited than for reference actives such as retinoids or vitamin C. Treat it as a solid supporting anti-aging ingredient, not as a replacement for those actives. Systemic exposure from topical use is negligible, so it can be used in pregnancy and breastfeeding. Tolerance is very good: irritation and allergy risk are low, suitable even for sensitive skin. It does not dry the skin and is not linked to pore clogging, so it fits well into maintenance routines.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Hydroxypropyl Tetrahydropyrantriol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Hydroxypropyl Tetrahydropyrantriol suits: normal, dry, combination, oily, sensitive.
An anti-aging active (Pro-Xylane).
The INCI name is Hydroxypropyl Tetrahydropyrantriol. It may also appear as: Гидроксипропил тетрагидропирантриол, Pro-Xylane.
Published: · updated: