EEvigrade
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Idebenone

Synthetic analog of ubiquinone (CoQ10) with higher stability. Works as an antioxidant and mitochondrial protector and has been studied in dermatology since the 2000s.

Anti-agingProtection

Evidence by route

Topical application

C

Weak evidence. In vitro data, open-label studies, or expert consensus.

Early studies show antioxidant protection of skin cells from UV stress. Large comparative RCTs are few, so reviews classify idebenone among «promising but not proven» antioxidants.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Unknown

Skin types

Suitable for

OilyDryCombinationNormal

Frequently asked questions

Is Idebenone safe during pregnancy?

Safety data for Idebenone during pregnancy is insufficient. Best avoided when in doubt.

What skin types is Idebenone for?

Idebenone suits: oily, dry, combination, normal.