A derivative of the dipeptide carnosine. An antioxidant that supports skin defense against oxidative stress. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
An antioxidant carnosine derivative. Safe.
N-acetylcarnosine (INCI: N-Acetylcarnosine) is an acetylated derivative of the dipeptide carnosine, more stable than the free form. In cosmetics it is used as an antioxidant: it helps curb free-radical damage and protein glycation, processes tied to skin aging. On efficacy a caveat is fair: most N-acetylcarnosine data come from ophthalmology, not skin. As a topical antioxidant it makes sense in a support role, but skin-specific dermatological evidence is thin. The reasonable view is a supporting ingredient within an antioxidant formula, with no promise of visible results on its own. Applied topically it has no systemic significance, so it can be used in pregnancy and breastfeeding. Tolerance is good. Irritation and allergy potential are low and it suits sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
N-Acetylcarnosine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
N-Acetylcarnosine suits: normal, dry, combination, oily, sensitive.
A derivative of the dipeptide carnosine.
The INCI name is N-Acetylcarnosine. It may also appear as: N-ацетилкарнозин, NAC.
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