A recombinant peptide. The maker links it to skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A recombinant peptide. Well tolerated; independent data limited.
This recombinant peptide from Nicotiana benthamiana (INCI Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-47) is a protein fragment made by biotechnology: the peptide gene is inserted into a tobacco plant, which then produces the molecule. In skincare it is positioned as an active for skin renewal and firmness. On efficacy we stay reserved. The manufacturer links the peptide to skin repair, but independent clinical data is still limited and the evidence base is modest. It reads more as a supporting ingredient in a formula than a standalone workhorse active. Do not expect visible rejuvenation from it. Used topically the peptide has no systemic relevance, so it can be used during pregnancy and breastfeeding without restriction. Tolerance is good. The irritation and allergy potential is low, which suits sensitive skin. Recombinant peptides come in purified form, and most people show no reaction.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-47 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-47 suits: normal, dry, combination, oily, sensitive.
A recombinant peptide.
The INCI name is Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-47. It may also appear as: Рекомбинантный пептид Nicotiana benthamiana.
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