Evigrade

Nicotiana Benthamiana Octapeptide-30

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana Benthamiana Octapeptide-30 is a recombinant eight-amino-acid peptide produced in the tobacco plant Nicotiana benthamiana, used as a plant-based biofactory. It appears in the INCI list under this full name. In a formula it is positioned as a signalling peptide aimed at anti-ageing goals. Here it is worth being honest about efficacy. The manufacturer links it to skin renewal and firmness, but independent data are limited and most of it comes from the company selling it. It counts as a supporting component within a well-built anti-ageing formula rather than an active with solid backing. The evidence base is still modest. Applied topically the molecule has very little systemic absorption, so it can be used during pregnancy and breastfeeding without concern. Tolerability is good. Both its irritant and allergenic potential are low, which makes it suitable for sensitive skin. There are no meaningful comedogenicity data, so it is not a concern for oily or acne-prone skin either.

Frequently asked questions

Is Nicotiana Benthamiana Octapeptide-30 safe during pregnancy?

Nicotiana Benthamiana Octapeptide-30 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana Octapeptide-30 for?

Nicotiana Benthamiana Octapeptide-30 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana Octapeptide-30 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana Octapeptide-30?

The INCI name is Nicotiana Benthamiana Octapeptide-30. It may also appear as: Octapeptide-30.

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