Evigrade

Nicotiana Benthamiana sh-Polypeptide-76

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana Benthamiana sh-Polypeptide-76 is a recombinant peptide produced biotechnologically in the tobacco plant Nicotiana benthamiana, used as a plant-based biofactory. It is added to anti-aging formulas as a conditioning ingredient, and the manufacturer links it with skin renewal and firmness. On efficacy let us be clear: independent data are scarce. Recombinant peptides look promising as a concept, but for now it is reasonable to treat it as a supporting ingredient, not an active with benefit proven in external studies. The brand story runs ahead of the evidence. Applied topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good. Irritation and allergy potential are low, which makes it suitable for sensitive skin. In cosmetic formulas most people show no reaction.

Frequently asked questions

Is Nicotiana Benthamiana sh-Polypeptide-76 safe during pregnancy?

Nicotiana Benthamiana sh-Polypeptide-76 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana sh-Polypeptide-76 for?

Nicotiana Benthamiana sh-Polypeptide-76 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana sh-Polypeptide-76 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana sh-Polypeptide-76?

The INCI name is Nicotiana Benthamiana sh-Polypeptide-76. It may also appear as: sh-Polypeptide-76, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76.

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