A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A biotech peptide. The maker links it to skin firmness; independent data limited.
Nicotiana Benthamiana sh-Polypeptide-76 is a recombinant peptide produced biotechnologically in the tobacco plant Nicotiana benthamiana, used as a plant-based biofactory. It is added to anti-aging formulas as a conditioning ingredient, and the manufacturer links it with skin renewal and firmness. On efficacy let us be clear: independent data are scarce. Recombinant peptides look promising as a concept, but for now it is reasonable to treat it as a supporting ingredient, not an active with benefit proven in external studies. The brand story runs ahead of the evidence. Applied topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good. Irritation and allergy potential are low, which makes it suitable for sensitive skin. In cosmetic formulas most people show no reaction.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana sh-Polypeptide-76 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana sh-Polypeptide-76 suits: normal, dry, combination, oily, sensitive.
A recombinant peptide grown in Nicotiana benthamiana tobacco.
The INCI name is Nicotiana Benthamiana sh-Polypeptide-76. It may also appear as: sh-полипептид-76, sh-Polypeptide-76, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76.
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