Nicotinamide Adenine Dinucleotide
A niacinamide-based coenzyme. The maker links it to cell energy metabolism and skin repair; independent data are limited. Well tolerated.
Evidence by route
Topical application
A functional active. Safe; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme involved in redox reactions and energy metabolism in every living cell. INCI: Nicotinamide Adenine Dinucleotide. In cosmetics it is marketed as an ingredient for cellular energy and anti-aging support. The biological role of NAD inside the cell is huge, but that is about metabolism inside the cell, while cosmetics act on the outside. Topical clinical data that applying NAD to skin gives a measurable anti-aging result are scarce, and claims lean on biochemical logic rather than human trials. So on this card it is a supporting component, not a lead active with a proven effect. Treat promises of cellular energy with restraint. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. Irritation and allergen potential are low.
Frequently asked questions
Is Nicotinamide Adenine Dinucleotide safe during pregnancy?
Nicotinamide Adenine Dinucleotide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Nicotinamide Adenine Dinucleotide for?
Nicotinamide Adenine Dinucleotide suits: normal, dry, combination, oily, sensitive.
What is Nicotinamide Adenine Dinucleotide and what does it do in cosmetics?
A niacinamide-based coenzyme.
What's the INCI name for Nicotinamide Adenine Dinucleotide?
The INCI name is Nicotinamide Adenine Dinucleotide. It may also appear as: NAD.
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