A niacinamide-based coenzyme. The maker links it to cell energy metabolism and skin repair; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A functional active. Safe; independent data limited.
Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme involved in redox reactions and energy metabolism in every living cell. INCI: Nicotinamide Adenine Dinucleotide. In cosmetics it is marketed as an ingredient for cellular energy and anti-aging support. The biological role of NAD inside the cell is huge, but that is about metabolism inside the cell, while cosmetics act on the outside. Topical clinical data that applying NAD to skin gives a measurable anti-aging result are scarce, and claims lean on biochemical logic rather than human trials. So on this card it is a supporting component, not a lead active with a proven effect. Treat promises of cellular energy with restraint. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. Irritation and allergen potential are low.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotinamide Adenine Dinucleotide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotinamide Adenine Dinucleotide suits: normal, dry, combination, oily, sensitive.
A niacinamide-based coenzyme.
The INCI name is Nicotinamide Adenine Dinucleotide. It may also appear as: Никотинамидадениндинуклеотид, NAD.
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