Oligopeptide-2
A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A synthetic peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Oligopeptide-2 is a short synthetic peptide added to serums and creams positioned for anti-aging and mature-skin care. On efficacy, it's worth being honest: the manufacturer links it to firmness and cell renewal, but independent data are scarce. Like many cosmetic peptides, its real ability to penetrate and produce a measurable change in skin is poorly demonstrated outside the supplier's own studies. At best it works as a supporting ingredient within a formula, not an active with solid clinical backing. Keep expectations modest. Topical use during pregnancy and breastfeeding poses no problem; cosmetic peptides are considered low systemic risk. Tolerance is high, with low irritation and allergy potential. Suitable for sensitive skin.
Frequently asked questions
Is Oligopeptide-2 safe during pregnancy?
Oligopeptide-2 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Oligopeptide-2 for?
Oligopeptide-2 suits: normal, dry, combination, oily, sensitive.
What is Oligopeptide-2 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Oligopeptide-2?
The INCI name is Oligopeptide-2.
See Oligopeptide-2 in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
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