Oligopeptide-4
A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A synthetic peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Oligopeptide-4 (INCI Oligopeptide-4) is a short synthetic peptide of several amino acids. In skincare it is positioned as a signal active linked to skin firmness and renewal. On efficacy we stay reserved. The manufacturer credits the peptide with an anti-ageing action, but independent clinical data is limited and the evidence base is modest. It reads more as a supporting ingredient in a formula's peptide blend than a standalone workhorse active. Do not expect a visible rejuvenating effect from it. Used topically the peptide has no systemic relevance, so it can be used during pregnancy and breastfeeding without restriction. Tolerance is good. The irritation and allergy potential is low, which suits sensitive skin. Synthetic peptides come in purified form, and most people show no reaction.
Frequently asked questions
Is Oligopeptide-4 safe during pregnancy?
Oligopeptide-4 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Oligopeptide-4 for?
Oligopeptide-4 suits: normal, dry, combination, oily, sensitive.
What is Oligopeptide-4 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Oligopeptide-4?
The INCI name is Oligopeptide-4.
See Oligopeptide-4 in a product composition right on the store page
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