A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A synthetic peptide. Well tolerated; independent data limited.
Oligopeptide-4 (INCI Oligopeptide-4) is a short synthetic peptide of several amino acids. In skincare it is positioned as a signal active linked to skin firmness and renewal. On efficacy we stay reserved. The manufacturer credits the peptide with an anti-ageing action, but independent clinical data is limited and the evidence base is modest. It reads more as a supporting ingredient in a formula's peptide blend than a standalone workhorse active. Do not expect a visible rejuvenating effect from it. Used topically the peptide has no systemic relevance, so it can be used during pregnancy and breastfeeding without restriction. Tolerance is good. The irritation and allergy potential is low, which suits sensitive skin. Synthetic peptides come in purified form, and most people show no reaction.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Oligopeptide-4 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Oligopeptide-4 suits: normal, dry, combination, oily, sensitive.
A synthetic peptide.
The INCI name is Oligopeptide-4. It may also appear as: Олигопептид-4.
Published: · updated: