Palmitoyl Oligopeptide
A synthetic lipopeptide. The maker links it to skin firmness and collagen support; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. The maker links it to skin firmness; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Palmitoyl Oligopeptide is a synthetic lipopeptide, a short amino-acid chain bound to palmitic acid for better penetration. Its INCI is Palmitoyl Oligopeptide. It goes into anti-ageing formulas on the idea of supporting firmness and collagen synthesis. The maker links the peptide with firmer skin, but independent data are sparse. View it as a supporting active with a modest evidence base, not a replacement for better-studied ingredients such as retinoids or vitamin C. It can accompany other actives, without expecting a dramatic change from it. Topically its systemic absorption is minimal, so it can be used during pregnancy and breastfeeding. Tolerance is good and irritation and allergy risk are low. It suits sensitive skin and is not comedogenic, so it fits oily skin too.
Frequently asked questions
Is Palmitoyl Oligopeptide safe during pregnancy?
Palmitoyl Oligopeptide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Palmitoyl Oligopeptide for?
Palmitoyl Oligopeptide suits: normal, dry, combination, oily, sensitive.
What is Palmitoyl Oligopeptide and what does it do in cosmetics?
A synthetic lipopeptide.
What's the INCI name for Palmitoyl Oligopeptide?
The INCI name is Palmitoyl Oligopeptide.
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