A peptide active. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. Well tolerated; independent data limited.
Palmitoyl tetrapeptide-10 (INCI: Palmitoyl Tetrapeptide-10) is a four amino acid peptide attached to palmitic fatty acid, which improves its affinity for the outer skin layers. It appears in serums and creams with anti-aging and soothing positioning. On efficacy, the manufacturer links it to firmer skin and better texture, but independent data are sparse and most studies come from the supplier itself. It is reasonable to treat it as a supporting active within a well-built formula, without expecting results on par with retinol or vitamin C. Topically, the molecular size and dose mean systemic uptake is minimal, so it can be applied during pregnancy and breastfeeding. Tolerance is good and the allergy potential is low. It suits sensitive skin. As with any new ingredient, a small forearm patch test helps if your skin reacts easily.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Palmitoyl Tetrapeptide-10 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Palmitoyl Tetrapeptide-10 suits: normal, dry, combination, oily, sensitive.
A peptide active.
The INCI name is Palmitoyl Tetrapeptide-10. It may also appear as: Пальмитоил тетрапептид-10.
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