Palmitoyl Tetrapeptide-10
A peptide active. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Palmitoyl tetrapeptide-10 (INCI: Palmitoyl Tetrapeptide-10) is a four amino acid peptide attached to palmitic fatty acid, which improves its affinity for the outer skin layers. It appears in serums and creams with anti-aging and soothing positioning. On efficacy, the manufacturer links it to firmer skin and better texture, but independent data are sparse and most studies come from the supplier itself. It is reasonable to treat it as a supporting active within a well-built formula, without expecting results on par with retinol or vitamin C. Topically, the molecular size and dose mean systemic uptake is minimal, so it can be applied during pregnancy and breastfeeding. Tolerance is good and the allergy potential is low. It suits sensitive skin. As with any new ingredient, a small forearm patch test helps if your skin reacts easily.
Frequently asked questions
Is Palmitoyl Tetrapeptide-10 safe during pregnancy?
Palmitoyl Tetrapeptide-10 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Palmitoyl Tetrapeptide-10 for?
Palmitoyl Tetrapeptide-10 suits: normal, dry, combination, oily, sensitive.
What is Palmitoyl Tetrapeptide-10 and what does it do in cosmetics?
A peptide active.
What's the INCI name for Palmitoyl Tetrapeptide-10?
The INCI name is Palmitoyl Tetrapeptide-10.
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