Marketing hexapeptide with claimed effect on collagen synthesis. Evidence base is predominantly manufacturer-sponsored.
Topical application
DVery weak or conflicting data.
Independent RCTs are essentially absent.
Hexapeptide-9 (Collaxyl) is a marketing hexapeptide from Vincience (now part of Ashland) with claimed effect on type IV collagen synthesis. Where applied. Anti-aging serums and creams (0.5-3% commercial complex). Evidence base. Manufacturer cites 28-day studies in 20 volunteers – improved firmness and elasticity. No independent peer-reviewed RCTs. The evidence base is predominantly manufacturer-sponsored. Safety. CIR has not made a separate assessment. Pregnancy – use with caution (UNKNOWN). Lactation – safe per manufacturer, no direct data.
Irritation potential
LowAllergen risk
LowPregnancy
CautionSuitable for
Use with caution
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Hexapeptide-9 should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
Hexapeptide-9 suits: normal, dry, oily, combination. Use with caution in: sensitive.
Marketing hexapeptide with claimed effect on collagen synthesis.
The INCI name is Hexapeptide-9. It may also appear as: Collaxyl.
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