Oxidized Glutathione
An oxidized form of the antioxidant glutathione. The maker links it to defense against oxidative stress; topical data are limited. Well tolerated.
Evidence by route
Topical application
An antioxidant component. Safe; data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Oxidized glutathione (INCI: Oxidized Glutathione) is the oxidized form of the tripeptide glutathione, an antioxidant molecule naturally present in cells. In cosmetics it is added with the idea of supporting defence against oxidative stress. Here the assessment has to be honest. The manufacturer links it to the skin's antioxidant protection, but data on topical use are scarce, and the existing skin-tone results mostly come from the reduced form and non-topical routes. As a topical active its backing is modest: it counts as a support ingredient, not one with a proven effect. Topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential. It suits sensitive skin.
Frequently asked questions
Is Oxidized Glutathione safe during pregnancy?
Oxidized Glutathione is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Oxidized Glutathione for?
Oxidized Glutathione suits: normal, dry, combination, oily, sensitive.
What is Oxidized Glutathione and what does it do in cosmetics?
An oxidized form of the antioxidant glutathione.
What's the INCI name for Oxidized Glutathione?
The INCI name is Oxidized Glutathione. It may also appear as: GSSG.
See Oxidized Glutathione in a product composition right on the store page
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