Acetyl sh-Hexapeptide-5 Amide Acetate
A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A synthetic peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Acetyl sh-hexapeptide-5 amide acetate (INCI: Acetyl sh-Hexapeptide-5 Amide Acetate) is a short-chain synthetic peptide. In a formula it is added as a signalling ingredient, and makers link it to firmness and skin renewal. It is worth tempering expectations. The case rests mainly on supplier data, while independent confirmation of clear clinical effects stays thin. We place it as a supporting active with a modest base, not a proven peptide. It may add value inside a formula but does not by itself guarantee a visible change. In topical use peptides of this size barely penetrate to a systemic level, so it can be used during pregnancy and breastfeeding without any foreseeable risk. Tolerance is good, with low irritation and allergy potential, suitable for sensitive skin. Reactions to synthetic peptides are uncommon.
Frequently asked questions
Is Acetyl sh-Hexapeptide-5 Amide Acetate safe during pregnancy?
Acetyl sh-Hexapeptide-5 Amide Acetate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Acetyl sh-Hexapeptide-5 Amide Acetate for?
Acetyl sh-Hexapeptide-5 Amide Acetate suits: normal, dry, combination, oily, sensitive.
What is Acetyl sh-Hexapeptide-5 Amide Acetate and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Acetyl sh-Hexapeptide-5 Amide Acetate?
The INCI name is Acetyl sh-Hexapeptide-5 Amide Acetate.
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