Lepidium Meyenii Root Extract

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Suitable for

Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Lepidium Meyenii Root Extract is derived from the root of Peruvian maca, traditionally cultivated in the high Andes. It contains macamides (signature fatty amides of maca), glucosinolates, flavonoids, phytosterols, minerals (zinc, selenium), and B vitamins. In Peruvian ethnopharmacology it is used as an adaptogen and stimulant. Where it is used. Cosmetics – antioxidant serums, mature-skin products, formulas with adaptogens and energy marketing positioning. Concentrations 0.5-3%. Bioenergetics and supplements – oral additives for libido, endurance, and tone. In Spain – niche natural brands Cantabria, Esdor, and imported Peruvian lines. Mechanism (topical). Antioxidant activity – free radical scavenging through flavonoids and phytosterols. Contains small amounts of minerals (zinc, selenium), but their bioavailability through topical application is limited. The marketing claim of an adaptogenic effect on skin is theoretical – there is no clear mechanism by which maca components would regulate keratinocyte stress response. Evidence base. Topical – evidence base D-F. No isolated clinical studies on cosmetic maca exist. Systemic oral intake – evidence base B for libido and sexual function (Cochrane review Shin 2010, at 1.5-3 g/day over 12 weeks), but this works through a different hormonal and whole-body adaptogenic mechanism. Cosmetics claim adaptogen power for skin – this is a marketing claim without clinical support. Safety. Pregnancy – CAUTION for oral use (no safety data at high doses). Topical use is likely safe, but clinical data are limited. Breastfeeding – similar. In patients with hormone-sensitive conditions (fibroids, endometriosis, estrogen-sensitive cancer), oral use is not recommended. Allergic reactions to maca (Brassicaceae) are rarely described. Practical notes. If a patient buys a cream with maca extract, that is marketing rather than a therapeutic component. Significant topical efficacy is unlikely. The role in formulas is an extra layer of adaptogen-concept storytelling, not a true active. For antioxidant protection, better-studied alternatives exist (vitamin C, niacinamide, resveratrol, tea flavonoids). Maca is not in the priority list of dermatologic actives.

Frequently asked questions