Evigrade

Nicotiana Benthamiana sh-Polypeptide-5

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana benthamiana sh-polypeptide-5 (same INCI) is a recombinant peptide produced in tobacco plants through biotechnology. The manufacturer presents it as a signaling peptide for skin renewal and firmness. Here it pays to be clear about efficacy. Signaling peptides are a promising category, but for this specific peptide the independent data is sparse and leans mostly on supplier information. Count it as a supporting active with still-limited evidence, not a guaranteed result. During pregnancy and breastfeeding it is fine to use topically. Tolerance is good: low irritation and low allergy potential, suitable for sensitive skin. An individual reaction is possible but uncommon.

Frequently asked questions

Is Nicotiana Benthamiana sh-Polypeptide-5 safe during pregnancy?

Nicotiana Benthamiana sh-Polypeptide-5 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana sh-Polypeptide-5 for?

Nicotiana Benthamiana sh-Polypeptide-5 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana sh-Polypeptide-5 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana sh-Polypeptide-5?

The INCI name is Nicotiana Benthamiana sh-Polypeptide-5. It may also appear as: sh-Polypeptide-5, Nicotiana Benthamiana Hexapeptide-40 sh-Polipeptido-5, Nicotiana Benthamiana Hexapeptide-40 sh-Polipeptido 5.

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