A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A biotech peptide. The maker links it to skin firmness; independent data limited.
Nicotiana benthamiana sh-polypeptide-5 (same INCI) is a recombinant peptide produced in tobacco plants through biotechnology. The manufacturer presents it as a signaling peptide for skin renewal and firmness. Here it pays to be clear about efficacy. Signaling peptides are a promising category, but for this specific peptide the independent data is sparse and leans mostly on supplier information. Count it as a supporting active with still-limited evidence, not a guaranteed result. During pregnancy and breastfeeding it is fine to use topically. Tolerance is good: low irritation and low allergy potential, suitable for sensitive skin. An individual reaction is possible but uncommon.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana sh-Polypeptide-5 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana sh-Polypeptide-5 suits: normal, dry, combination, oily, sensitive.
A recombinant peptide grown in Nicotiana benthamiana tobacco.
The INCI name is Nicotiana Benthamiana sh-Polypeptide-5. It may also appear as: sh-полипептид-5, sh-Polypeptide-5, Nicotiana Benthamiana Hexapeptide-40 sh-Polipeptido-5.
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