Evigrade

Nicotiana Benthamiana Hexapeptide-40

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana benthamiana hexapeptide-40 (same INCI) is a recombinant peptide produced in tobacco plants through biotechnology. The manufacturer proposes it as a signaling peptide tied to skin renewal and firmness. It pays to be clear about efficacy. Signaling peptides are a promising line, but for this hexapeptide the independent data is sparse and rests mostly on the supplier. Count it as a supporting active with still-limited evidence, not an assured result. During pregnancy and breastfeeding it is fine to use topically. Tolerance is good: low irritation and low allergy potential, suitable for sensitive skin. An individual reaction is possible but uncommon.

Frequently asked questions

Is Nicotiana Benthamiana Hexapeptide-40 safe during pregnancy?

Nicotiana Benthamiana Hexapeptide-40 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana Hexapeptide-40 for?

Nicotiana Benthamiana Hexapeptide-40 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana Hexapeptide-40 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana Hexapeptide-40?

The INCI name is Nicotiana Benthamiana Hexapeptide-40. It may also appear as: Hexapeptide-40, Nicotiana Benthamiana Hexapeptide 40.

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