Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6
A biotech peptide grown in a plant system. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A biotech peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 is a biotech peptide produced in a plant system, the Nicotiana benthamiana plant, through recombinant expression. It is used in anti-aging formulas with a promise of firmness and skin renewal. The efficacy assessment calls for restraint. The biotech origin sounds advanced, but it is the manufacturer who links the peptide with these benefits, and independent data are limited. It behaves as a supporting active with a modest evidence base. The novelty of the production method does not equal proven clinical results. In topical use systemic relevance is minimal, so it can be used during pregnancy and breastfeeding. Irritation and allergy potential are low, which makes it suitable for sensitive skin. Most people tolerate it without discomfort.
Frequently asked questions
Is Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 safe during pregnancy?
Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 for?
Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 suits: normal, dry, combination, oily, sensitive.
What is Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6 and what does it do in cosmetics?
A biotech peptide grown in a plant system.
What's the INCI name for Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6?
The INCI name is Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-6.
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