Tetrahydrodiferuloylmethane
A stable curcumin derivative. It works as an antioxidant and helps even out skin tone. Well tolerated.
Evidence by route
Topical application
An antioxidant active. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Tetrahydrodiferuloylmethane is a hydrogenated, more stable derivative of curcumin. Its INCI is Tetrahydrodiferuloylmethane. In a formula it works as an antioxidant and is included on the idea of helping even out skin tone. Compared with raw curcumin it has the advantage of being nearly colourless and more light-stable, which makes it practical in cosmetics. The antioxidant evidence is reasonable, while the effect on tone is more modest and should be expected as support, not as a strong brightener. Topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good and irritation and allergy risk are low. It suits sensitive skin and is not comedogenic, so it fits oily or acne-prone skin too.
Frequently asked questions
Is Tetrahydrodiferuloylmethane safe during pregnancy?
Tetrahydrodiferuloylmethane is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Tetrahydrodiferuloylmethane for?
Tetrahydrodiferuloylmethane suits: normal, dry, combination, oily, sensitive.
What is Tetrahydrodiferuloylmethane and what does it do in cosmetics?
A stable curcumin derivative.
What's the INCI name for Tetrahydrodiferuloylmethane?
The INCI name is Tetrahydrodiferuloylmethane. It may also appear as: Tetrahydrocurcumin.
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