Metabolites of a thermophilic bacterium from hot springs. Protect the skin from heat and UV stress and support mitochondria. Pregnancy-safe.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Protective antioxidant from a thermophilic bacterium. Moderate evidence (in vivo + small RCTs).
Thermus thermophilus ferment is a fermentate of metabolites of the thermophilic bacterium Thermus thermophilus, isolated from deep-sea hydrothermal vents. INCI: Thermus Thermophillus Ferment. Sold under the Venuceane brand (Sederma). In cosmetics it works as a protective antioxidant. The bacterium has evolved to extreme temperatures and oxidative stress, and its metabolites contain heat-stable enzymes (superoxide dismutase, catalase) and low-molecular-weight antioxidants. On the skin the ingredient protects keratinocyte mitochondria from UV and infrared damage and reduces matrix metalloproteinase synthesis. It is used in sunscreens, anti-aging creams, products for mature and damaged skin, and after-sun products. Use levels run from 1 to 3%. Pregnancy safety. Skin absorption into the systemic circulation is minimal. Safety is confirmed by the manufacturer. Skin profile. Very low irritation and allergen potential. Non-comedogenic. Suitable for all skin types, including very sensitive. Moderate evidence (B) – in vitro, in vivo and small clinical data from Sederma.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Thermus Thermophillus Ferment is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Thermus Thermophillus Ferment suits: normal, dry, combination, oily, sensitive.
Metabolites of a thermophilic bacterium from hot springs.
On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
The INCI name is Thermus Thermophillus Ferment. It may also appear as: Thermus Thermophilus Ferment, Venuceane, Фермент Thermus thermophilus.
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