Tocopheryl Nicotinate
A derivative of vitamin E and niacin. It supports antioxidant defense and skin tone. Well tolerated.
Evidence by route
Topical application
An active vitamin E derivative. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Tocopheryl nicotinate (INCI: Tocopheryl Nicotinate) is an ester that joins vitamin E and nicotinic acid (niacin). On the skin it releases gradually to deliver both parts: vitamin E as an antioxidant that protects lipids, and the niacin fraction linked to tone and skin microcirculation. It appears in anti-aging creams and repair formulas. As an active it has a reasonable base. Vitamin E is a well-documented antioxidant and niacin derivatives have support for barrier and radiance, though the specific evidence for this particular ester is more limited than for each vitamin on its own. It works as a good supporting antioxidant. For topical use there is no relevant systemic risk. It can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential. It is not noted as comedogenic or drying.
Frequently asked questions
Is Tocopheryl Nicotinate safe during pregnancy?
Tocopheryl Nicotinate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Tocopheryl Nicotinate for?
Tocopheryl Nicotinate suits: normal, dry, combination, oily, sensitive.
What is Tocopheryl Nicotinate and what does it do in cosmetics?
A derivative of vitamin E and niacin.
What's the INCI name for Tocopheryl Nicotinate?
The INCI name is Tocopheryl Nicotinate.
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Tocotrienols, Tretinoin, Trifluoroacetyl Tripeptide-2, Tripeptide-1, Bee Venom, Gluconolactone (PHA), Nicotiana Benthamiana sh-Polypeptide-15, Pteris Multifida Extract
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