A plant alkaloid antioxidant. The maker links it to evening skin tone and free-radical protection; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A brightening antioxidant. Safe; independent data limited.
Diacetyl Boldine is an acetylated derivative of boldine, a plant alkaloid with antioxidant action. Its INCI is Diacetyl Boldine. It is included in formulas on the idea of evening out tone and protecting against free radicals. The maker links the ingredient with a more even tone, but independent data are sparse. View it as a supporting active with a modest evidence base: it may add to a formula's antioxidant action, without expecting a marked change from it alone. Topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good and irritation and allergy risk are low. It suits sensitive skin and is not comedogenic, so it fits oily or acne-prone skin too.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Diacetyl Boldine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Diacetyl Boldine suits: normal, dry, combination, oily, sensitive.
A plant alkaloid antioxidant.
The INCI name is Diacetyl Boldine. It may also appear as: Диацетил болдин.
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