Evigrade

Galactonic Acid

Polyhydroxy acid, a structural sibling of lactobionic acid. Used in very gentle acid formulations for sensitive skin and post-procedure recovery. A larger molecule than AHAs, it acts mostly at the surface without provoking stinging or redness. Moisturising effect from multiple hydroxyl groups.

Evidence by route

C

Topical application

Clinical data on isolated galactonic acid are scarce. Most PHA research covers gluconolactone and lactobionic acid. Within multi-PHA serums it adds to the overall gentle exfoliation.

  • Green BA et al. Clin Dermatol. 2009;27(5):495-501. PMID 19695482
How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Sensitive

About this ingredient

Galactonic acid is a polyhydroxy acid (PHA), a structural sibling of lactobionic acid. Obtained by oxidation of galactose. Where applied. Very gentle exfoliators for sensitive skin (4-15%), serums and toners, post-procedure products. Often combined with gluconolactone and lactobionic acid – NeoStrata Restore, Exuviance Gentle lines. Advantages over AHAs. The molecule is larger than glycolic and lactic acid – penetrates slowly, exfoliates surface only. No stinging or redness. Does not photosensitize (Edison 2004). Additionally hydrates thanks to multiple hydroxyl groups. Evidence base. PHAs as a class have been studied in RCTs: Green 2009 in 200 photoaging patients showed tone and texture improvement over 12 weeks of 10% PHA, without irritation. Direct studies of galactonic acid alone are few; data are largely extrapolated from gluconolactone and lactobionic acid. Safety. CIR confirmed safety. Hypoallergenic, non-comedogenic. Irritation is rare and mild. Pregnancy and lactation – safe. One of the few first-line exfoliants in pregnancy (alongside gluconolactone and azelaic acid).

Frequently asked questions

Is Galactonic Acid safe during pregnancy?

Galactonic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Galactonic Acid for?

Galactonic Acid suits: normal, dry, combination, sensitive.

What is Galactonic Acid and what does it do in cosmetics?

Polyhydroxy acid, a structural sibling of lactobionic acid.

What's the INCI name for Galactonic Acid?

The INCI name is Galactonic Acid. It may also appear as: Galactose, Bionic Acid.

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