INCI: Gluconolactone
Polyhydroxy acid, a structural sibling of lactobionic acid. Used in very gentle acid formulations for sensitive skin and post-procedure recovery. A larger molecule than AHAs, it acts mostly at the surface without provoking stinging or redness. Moisturising effect from multiple hydroxyl groups.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Clinical data on isolated galactonic acid are scarce. Most PHA research covers gluconolactone and lactobionic acid. Within multi-PHA serums it adds to the overall gentle exfoliation.
Galactonic acid is a polyhydroxy acid (PHA), a structural sibling of lactobionic acid. Obtained by oxidation of galactose. Where applied. Very gentle exfoliators for sensitive skin (4-15%), serums and toners, post-procedure products. Often combined with gluconolactone and lactobionic acid – NeoStrata Restore, Exuviance Gentle lines. Advantages over AHAs. The molecule is larger than glycolic and lactic acid – penetrates slowly, exfoliates surface only. No stinging or redness. Does not photosensitize (Edison 2004). Additionally hydrates thanks to multiple hydroxyl groups. Evidence base. PHAs as a class have been studied in RCTs: Green 2009 in 200 photoaging patients showed tone and texture improvement over 12 weeks of 10% PHA, without irritation. Direct studies of galactonic acid alone are few; data are largely extrapolated from gluconolactone and lactobionic acid. Safety. CIR confirmed safety. Hypoallergenic, non-comedogenic. Irritation is rare and mild. Pregnancy and lactation – safe. One of the few first-line exfoliants in pregnancy (alongside gluconolactone and azelaic acid).
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Galactonic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Galactonic Acid suits: normal, dry, combination, sensitive.
Polyhydroxy acid, a structural sibling of lactobionic acid.
The INCI name is Gluconolactone. It may also appear as: Galactonic Acid, Galactose, Bionic Acid.
Published: · updated: