Glutamylamidoethyl Imidazole
A synthetic histidine-derived active. The maker links it to evening skin tone; independent data are limited. Well tolerated.
Evidence by route
Topical application
A brightening active. Safe; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Glutamylamidoethyl Imidazole is a synthetic active, a derivative related to the amino acid histidine. Its INCI name is Glutamylamidoethyl Imidazole. In a formula it is included in products aimed at evening out skin tone. On efficacy it is worth being plain. The manufacturer links it to a more even tone, but independent data are thin. For now it fits better as a supportive active with a modest evidence base than as a proven fix for pigmentation. Do not expect marked results. Applied topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is high, with a low irritation and allergy potential, and it suits sensitive skin. Most people see no reaction.
Frequently asked questions
Is Glutamylamidoethyl Imidazole safe during pregnancy?
Glutamylamidoethyl Imidazole is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Glutamylamidoethyl Imidazole for?
Glutamylamidoethyl Imidazole suits: normal, dry, combination, oily, sensitive.
What is Glutamylamidoethyl Imidazole and what does it do in cosmetics?
A synthetic histidine-derived active.
What's the INCI name for Glutamylamidoethyl Imidazole?
The INCI name is Glutamylamidoethyl Imidazole.
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