Evigrade

Tetrahydrobisdemethoxydiferuloylmethane

A colorless curcumin derivative. An antioxidant that soothes and supports even tone. Well tolerated.

Evidence by route

B

Topical application

An antioxidant curcumin derivative. Well tolerated.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

This ingredient (INCI: Tetrahydrobisdemethoxydiferuloylmethane) is a hydrogenated, colorless derivative of curcumin, the pigment of turmeric. Without the intense yellow color it can be used in cosmetics without tinting the formula, while keeping the antioxidant character. It helps curb oxidative stress, soothes the skin and supports a more even tone. On efficacy, curcuminoids are of interest as antioxidants and soothing agents, with data mostly from the lab and a few small skin studies. It is a reasonable supporting active within an antioxidant formula, not a treatment that erases dark spots or wrinkles on its own. Applied topically it has no systemic significance, so it can be used in pregnancy and breastfeeding. Tolerance is good. Irritation and allergy potential are low, which makes it suitable for sensitive and reactive skin.

Frequently asked questions

Is Tetrahydrobisdemethoxydiferuloylmethane safe during pregnancy?

Tetrahydrobisdemethoxydiferuloylmethane is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Tetrahydrobisdemethoxydiferuloylmethane for?

Tetrahydrobisdemethoxydiferuloylmethane suits: normal, dry, combination, oily, sensitive.

What is Tetrahydrobisdemethoxydiferuloylmethane and what does it do in cosmetics?

A colorless curcumin derivative.

What's the INCI name for Tetrahydrobisdemethoxydiferuloylmethane?

The INCI name is Tetrahydrobisdemethoxydiferuloylmethane. It may also appear as: White Turmeric Derivative.

See Tetrahydrobisdemethoxydiferuloylmethane in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar role in the formula

Explore by category

Anti-aging, Soothing, Brightening

Published: · updated: