Nicotiana Benthamiana sh-Polypeptide-45
A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Evidence by route
Topical application
A biotech peptide. The maker links it to skin firmness; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
sh-Polypeptide-45 is a biotech growth-factor peptide, in this version produced in the plant Nicotiana benthamiana. INCI: Nicotiana Benthamiana sh-Polypeptide-45. In skin, growth factors take part in cell division and renewal. In a formula it works as an active component with a claimed regenerating and anti-aging action. Topical growth factors are under study, early data exist, but the evidence base is limited, penetration of the large molecule is low, and stimulation of cell division is treated with caution. It is a promising but supporting active with an incomplete base, not a treatment with a proven result. Pregnancy safety. Topical use, no evidence of harm, but growth factors are used with caution during pregnancy. Tolerance. Irritation and allergen potential are low.
Frequently asked questions
Is Nicotiana Benthamiana sh-Polypeptide-45 safe during pregnancy?
Nicotiana Benthamiana sh-Polypeptide-45 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Nicotiana Benthamiana sh-Polypeptide-45 for?
Nicotiana Benthamiana sh-Polypeptide-45 suits: normal, dry, combination, oily, sensitive.
What is Nicotiana Benthamiana sh-Polypeptide-45 and what does it do in cosmetics?
A recombinant peptide grown in Nicotiana benthamiana tobacco.
What's the INCI name for Nicotiana Benthamiana sh-Polypeptide-45?
The INCI name is Nicotiana Benthamiana sh-Polypeptide-45. It may also appear as: sh-Polypeptide-45.
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