Evigrade

Nicotiana Benthamiana sh-Polypeptide-86

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana Benthamiana sh-Polypeptide-86 is a recombinant peptide produced in the tobacco plant Nicotiana benthamiana, a method that lets makers produce human-identical proteins without animal sourcing. In serums and creams it sits in the anti-aging category. Here it is worth being honest about the evidence. The manufacturer links the peptide to skin renewal and firmness, but independent data are scarce. Treat it as a supporting component with modest backing, not as an active with proven efficacy on the level of a retinoid or vitamin C. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, which makes it suitable for sensitive skin.

Frequently asked questions

Is Nicotiana Benthamiana sh-Polypeptide-86 safe during pregnancy?

Nicotiana Benthamiana sh-Polypeptide-86 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana sh-Polypeptide-86 for?

Nicotiana Benthamiana sh-Polypeptide-86 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana sh-Polypeptide-86 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana sh-Polypeptide-86?

The INCI name is Nicotiana Benthamiana sh-Polypeptide-86. It may also appear as: sh-Polypeptide-86, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-86.

See Nicotiana Benthamiana sh-Polypeptide-86 in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar role in the formula

Explore by category

Anti-aging

Published: · updated: