A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A biotech peptide. The maker links it to skin firmness; independent data limited.
Nicotiana Benthamiana sh-Polypeptide-86 is a recombinant peptide produced in the tobacco plant Nicotiana benthamiana, a method that lets makers produce human-identical proteins without animal sourcing. In serums and creams it sits in the anti-aging category. Here it is worth being honest about the evidence. The manufacturer links the peptide to skin renewal and firmness, but independent data are scarce. Treat it as a supporting component with modest backing, not as an active with proven efficacy on the level of a retinoid or vitamin C. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, which makes it suitable for sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana sh-Polypeptide-86 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana sh-Polypeptide-86 suits: normal, dry, combination, oily, sensitive.
A recombinant peptide grown in Nicotiana benthamiana tobacco.
The INCI name is Nicotiana Benthamiana sh-Polypeptide-86. It may also appear as: sh-полипептид-86, sh-Polypeptide-86, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-86.
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