Alpha Lipoic Acid
INCI: Thioctic Acid
Amphiphilic antioxidant soluble in both water and oils. Skincare promises «universal anti-aging protection»; clinical studies more often show a moderate effect.
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Small RCTs show moderate improvement in fine lines and texture. At concentrations above 5% it causes tingling and mild redness, so sensitive skin handles it poorly.
Tolerability and safety
Irritation potential
MediumAllergen risk
LowPregnancy
UnknownSkin types
Suitable for
Use with caution
Frequently asked questions
Is Alpha Lipoic Acid safe during pregnancy?
Safety data for Alpha Lipoic Acid during pregnancy is insufficient. Best avoided when in doubt.
What skin types is Alpha Lipoic Acid for?
Alpha Lipoic Acid suits: oily, combination, normal. Use with caution in: sensitive.
Can Alpha Lipoic Acid irritate the skin?
Alpha Lipoic Acid has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.