Evigrade

Resveratrol Dimethyl Ether

A stable resveratrol derivative. It works as an antioxidant and helps protect skin from free radicals. Well tolerated.

Evidence by route

B

Topical application

An antioxidant active. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Resveratrol Dimethyl Ether (pterostilbene) is a derivative of resveratrol, a plant stilbene. INCI: Resveratrol Dimethyl Ether. Two methyl groups make the molecule more stable and more fat-soluble than plain resveratrol, so it holds up better in a formula and penetrates skin more readily. In a formula it works as an antioxidant: it neutralizes free radicals and supports defense against oxidative stress. The antioxidant rationale is solid, but topical clinical data on a standalone skincare result are limited, so it is a supporting active rather than a treatment with a large evidence base. Pregnancy safety. Topical use is systemically negligible, with no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.

Frequently asked questions

Is Resveratrol Dimethyl Ether safe during pregnancy?

Resveratrol Dimethyl Ether is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Resveratrol Dimethyl Ether for?

Resveratrol Dimethyl Ether suits: normal, dry, combination, oily, sensitive.

What is Resveratrol Dimethyl Ether and what does it do in cosmetics?

A stable resveratrol derivative.

What's the INCI name for Resveratrol Dimethyl Ether?

The INCI name is Resveratrol Dimethyl Ether. It may also appear as: Pterostilbene.

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