A short peptide modeled on a collagen fragment. The maker links it to skin firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. Well tolerated; data limited.
Tripeptide-29 is a very short peptide whose sequence mimics a fragment of the collagen chain. In cosmetics it goes into anti-aging formulas as a signal meant to support firmness and visible elasticity. On efficacy, the evidence is modest. The collagen-mimetic peptide logic is plausible, but solid independent studies confirming a standalone clinical effect are lacking. It works as a supporting component within a formula, useful in combination rather than an active that guarantees results on its own. Applied topically it does not reach meaningful systemic levels, so use during pregnancy and breastfeeding is considered fine. Tolerance is good, with low irritation potential and low allergy risk. It suits sensitive skin. For reactive skin, a gradual introduction remains the more comfortable choice.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Tripeptide-29 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Tripeptide-29 suits: normal, dry, combination, oily, sensitive.
A short peptide modeled on a collagen fragment.
The INCI name is Tripeptide-29. It may also appear as: Трипептид-29.
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