Tripeptide-29
A short peptide modeled on a collagen fragment. The maker links it to skin firmness; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. Well tolerated; data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Tripeptide-29 is a very short peptide whose sequence mimics a fragment of the collagen chain. In cosmetics it goes into anti-aging formulas as a signal meant to support firmness and visible elasticity. On efficacy, the evidence is modest. The collagen-mimetic peptide logic is plausible, but solid independent studies confirming a standalone clinical effect are lacking. It works as a supporting component within a formula, useful in combination rather than an active that guarantees results on its own. Applied topically it does not reach meaningful systemic levels, so use during pregnancy and breastfeeding is considered fine. Tolerance is good, with low irritation potential and low allergy risk. It suits sensitive skin. For reactive skin, a gradual introduction remains the more comfortable choice.
Frequently asked questions
Is Tripeptide-29 safe during pregnancy?
Tripeptide-29 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Tripeptide-29 for?
Tripeptide-29 suits: normal, dry, combination, oily, sensitive.
What is Tripeptide-29 and what does it do in cosmetics?
A short peptide modeled on a collagen fragment.
What's the INCI name for Tripeptide-29?
The INCI name is Tripeptide-29.
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