A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A synthetic peptide. Well tolerated; independent data limited.
Diaminopropionoyl Tripeptide-33 (INCI Diaminopropionoyl Tripeptide-33) is a synthetic tripeptide with an attached diaminopropionic acid residue. It is added to anti-ageing formulas as a signalling ingredient that, by the developer's design, supports firmness and skin renewal. On efficacy, the stance is cautious. Most data come from the raw-material supplier, with little independent clinical work. This is a supporting ingredient in a formula, not a proven standalone active. It may strengthen the overall result of a routine, but it carries no promises on its own. During pregnancy and breastfeeding it can be used. The peptide molecule is large, it does not penetrate the skin systemically when applied topically, and there are no restrictions. Tolerance is good. The irritation potential is low, the allergy risk is low, and the ingredient suits sensitive skin. Peptides of this class behave calmly even on reactive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Diaminopropionoyl Tripeptide-33 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Diaminopropionoyl Tripeptide-33 suits: normal, dry, combination, oily, sensitive.
A synthetic peptide.
The INCI name is Diaminopropionoyl Tripeptide-33. It may also appear as: Диаминопропионоил трипептид-33.
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