Diaminopropionoyl Tripeptide-33
A synthetic peptide. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Evidence by route
Topical application
A synthetic peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Diaminopropionoyl Tripeptide-33 (INCI Diaminopropionoyl Tripeptide-33) is a synthetic tripeptide with an attached diaminopropionic acid residue. It is added to anti-ageing formulas as a signalling ingredient that, by the developer's design, supports firmness and skin renewal. On efficacy, the stance is cautious. Most data come from the raw-material supplier, with little independent clinical work. This is a supporting ingredient in a formula, not a proven standalone active. It may strengthen the overall result of a routine, but it carries no promises on its own. During pregnancy and breastfeeding it can be used. The peptide molecule is large, it does not penetrate the skin systemically when applied topically, and there are no restrictions. Tolerance is good. The irritation potential is low, the allergy risk is low, and the ingredient suits sensitive skin. Peptides of this class behave calmly even on reactive skin.
Frequently asked questions
Is Diaminopropionoyl Tripeptide-33 safe during pregnancy?
Diaminopropionoyl Tripeptide-33 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Diaminopropionoyl Tripeptide-33 for?
Diaminopropionoyl Tripeptide-33 suits: normal, dry, combination, oily, sensitive.
What is Diaminopropionoyl Tripeptide-33 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Diaminopropionoyl Tripeptide-33?
The INCI name is Diaminopropionoyl Tripeptide-33.
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