A peptide active. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. Well tolerated; independent data limited.
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide known by the trade name SYN-AKE. INCI: Dipeptide Diaminobutyroyl Benzylamide Diacetate. Its structure was modeled on a snake-venom component, and marketing presents it as a topical alternative to botulinum toxin injections for smoothing expression lines. The claimed mechanism is a mild relaxation of muscle contraction. The evidence base is mostly manufacturer studies, independent clinical data are limited, and the effect is mild and reversible. It is a supporting active rather than a botox equivalent. Pregnancy safety. Topical use, low peptide systemic absorption, no evidence of harm, but during pregnancy actives with a claimed neuromuscular action are treated with caution. Tolerance. Irritation and allergen potential are low.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Dipeptide Diaminobutyroyl Benzylamide Diacetate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Dipeptide Diaminobutyroyl Benzylamide Diacetate suits: normal, dry, combination, oily, sensitive.
A peptide active.
The INCI name is Dipeptide Diaminobutyroyl Benzylamide Diacetate. It may also appear as: Дипептид диаминобутироил бензиламид диацетат, Syn-Ake.
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