Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
A synthetic muscle-relaxing peptide. The maker links it to smoothing expression lines; independent data are limited. Well tolerated.
Evidence by route
Topical application
A synthetic peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate is a synthetic peptide that the cosmetic sector describes as a topical muscle relaxant (an expression-line "softener"). The manufacturer links it to smoother expression wrinkles by reducing the skin's repeated micro-contraction. On effectiveness it is worth keeping expectations measured. The idea of gently mimicking the botulinum toxin effect topically is appealing, but most of the data come from the manufacturer and independent evidence is scarce. It may give a modest visual improvement in fine lines with consistent use; it does not replace a medical procedure or match its result. Applied topically its systemic absorption is minimal, so it can be used during pregnancy and breastfeeding. Tolerability is good, with low irritation and allergy potential. It suits sensitive skin and is usually applied without discomfort at use levels.
Frequently asked questions
Is Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate safe during pregnancy?
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate for?
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate suits: normal, dry, combination, oily, sensitive.
What is Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate and what does it do in cosmetics?
A synthetic muscle-relaxing peptide.
What's the INCI name for Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate?
The INCI name is Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate. It may also appear as: SYN-AKE.
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