Adenosine
Natural nucleoside acting via skin adenosine receptors. Stimulates collagen synthesis and improves skin firmness.
Anti-aging
Evidence by route
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Several small clinical studies at 0.04% show modest wrinkle reduction. Manufacturer-sponsored data predominate. Independent large RCTs are absent. Mechanism of collagenogenesis stimulation via A2a receptors is established in vitro.
- Lee KS et al. Arch Dermatol Res. 2009;301(4):305-313.
Working concentrations
0.04%
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
UnknownSkin types
Suitable for
NormalDrySensitiveCombination
Frequently asked questions
Is Adenosine safe during pregnancy?
Safety data for Adenosine during pregnancy is insufficient. Best avoided when in doubt.
What skin types is Adenosine for?
Adenosine suits: normal, dry, sensitive, combination.