Epidermal Growth Factor (EGF)
INCI: sh-Oligopeptide-1
53-amino-acid peptide that stimulates keratinocyte and fibroblast proliferation. Used in post-procedure care and anti-aging products.
Anti-agingSoothing
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Small clinical studies show improved wound healing and skin texture. Penetration through intact stratum corneum is limited by the large molecular size. Long-term safety of systemic exposure is not established.
- Esquirol-Caussa J et al. J Cosmet Laser Ther. 2012;14(6):253-259.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
UnknownSkin types
Suitable for
NormalDrySensitiveCombination
Frequently asked questions
Is Epidermal Growth Factor (EGF) safe during pregnancy?
Safety data for Epidermal Growth Factor (EGF) during pregnancy is insufficient. Best avoided when in doubt.
What skin types is Epidermal Growth Factor (EGF) for?
Epidermal Growth Factor (EGF) suits: normal, dry, sensitive, combination.