An oil-soluble antioxidant. It protects the formula and skin from oxidation and supports an even tone. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
An antioxidant. Safe at cosmetic levels.
Dimethylmethoxy Chromanol is a lipophilic antioxidant from the chromanol family, structurally related to vitamin E. It's used in serums and creams to protect both the formula and the skin from oxidation. On efficacy: an antioxidant with a reasonable rationale. In vitro data show it quenches several radical types (both lipid and water phase) and helps keep a more even tone by limiting oxidative damage. It works as a supporting ingredient in an antioxidant system; on its own it doesn't replace sunscreen or proven brightening actives. The contribution is real but best positioned as an adjunct. Topical use during pregnancy and breastfeeding poses no problem. Tolerance is high, with low irritation and allergy potential. Suitable for sensitive skin. Not comedogenic at usual levels.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Dimethylmethoxy Chromanol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Dimethylmethoxy Chromanol suits: normal, dry, combination, oily, sensitive.
An oil-soluble antioxidant.
The INCI name is Dimethylmethoxy Chromanol. It may also appear as: Диметилметокси хроманол, Dimethylmetoxy Chromanol.
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