Ubiquinone (CoQ10)
INCI: Ubiquinone
Coenzyme involved in mitochondrial respiration. Its skin levels decline with age. An antioxidant protecting cell membranes from lipid peroxidation.
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Pilot clinical studies show wrinkle reduction and texture improvement with prolonged use. Antioxidant activity confirmed in vitro. No large independent RCTs. Penetration through the stratum corneum is limited – works better in nano-formulations.
- Hoppe U et al. Biofactors. 1999;9(2-4):371-378.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Ubiquinone (CoQ10) safe during pregnancy?
Ubiquinone (CoQ10) is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Ubiquinone (CoQ10) for?
Ubiquinone (CoQ10) suits: normal, dry, sensitive, combination.