Ascorbyl Palmitate
Lipid-soluble ester of vitamin C with palmitic acid. More stable than L-ascorbic acid, does not require acidic pH, and fits oil and emulsion formulas. However, hydrolysis in skin is limited and true vitamin C bioactivity is reduced. Often used as an antioxidant to stabilise oils in formulation.
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
More stable than L-ascorbic acid in formulation, but clinical data for photoageing and pigmentation are significantly weaker. In head-to-head comparisons with L-ascorbic acid it is inferior for brightening and collagen stimulation. In certain formulas it is still useful as an antioxidant to protect oils from oxidation.
- Pinnell SR et al. Dermatol Surg. 2001;27(2):137-142.
- Austria R et al. J Pharm Biomed Anal. 1997;15(6):795-801.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Ascorbyl Palmitate safe during pregnancy?
Ascorbyl Palmitate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Ascorbyl Palmitate for?
Ascorbyl Palmitate suits: normal, dry, combination, sensitive.