EEvigrade
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Ivermectin (topical)

INCI: Ivermectin

Topical antiparasitic agent that works against Demodex mites and rosacea inflammation. Galderma markets it as Soolantra.

Acne

Evidence by route

Topical application

A

Proven efficacy. Two or more independent RCTs with instrumental endpoints.

Large RCTs show superiority of ivermectin 1% over metronidazole 0.75% in papulo-pustular rosacea. Good tolerance in long-term therapy.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Caution

Frequently asked questions

Is Ivermectin (topical) safe during pregnancy?

Ivermectin (topical) should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.