Octocrylene
UVB and partial UVA filter that stabilizes avobenzone in SPF formulas. During prolonged storage it slowly turns into benzophenone with a limited toxicology base.
Evidence by route
Topical application
A 2021 study showed that octocrylene in sunscreens approaching expiry forms benzophenone in meaningful concentrations. For sensitive skin formulas with mineral filters are safer.
How to read tiers A–F
- DNo data, or very weak or conflicting data
Tolerability and safety
- Irritation potential
- Medium
- Allergen risk
- Moderate
- Pregnancy
- Avoid
- Suitable for
- Normal
- Use with caution
- Sensitive
Combinations with other ingredients
About this ingredient
Octocrylene is a synthetic organic UV filter, the 2-ethylhexyl ester of 2-cyano-3,3-diphenylacrylic acid. Covers UVB and partly UVA2 (absorption peak 303 nm). Often used as an avobenzone photostabilizer – without it avobenzone breaks down under UV within 30-60 minutes. Where applied. Sunscreens (up to 10% in EU and US, up to 8% in Canada), SPF makeup (foundations, BB creams, lipsticks). Benzophenone controversy 2021. The Sayre et al. study (Chem Res Toxicol, 2021) showed that during prolonged storage (>1 year at room temperature) octocrylene degrades into benzophenone – a potential endocrine disruptor (FDA TEA). Cosmetic manufacturers shifted formulations to stabilized variants after the publication, but older batches may contain meaningful benzophenone amounts. Safety. CIR/SCCS confirm safety at concentrations up to 10%. Systemic absorption through intact skin was reported in FDA Matta study (JAMA 2020) – octocrylene is detected in plasma after maximal application to 75% body surface area, but clinical significance has not been established. Non-comedogenic. Rare allergic reactions, mostly photocontact dermatitis. Pregnancy and lactation – acceptable. Despite systemic absorption reports, pregnant women use octocrylene SPF in practice – UV protection benefit substantially exceeds the theoretical risk. Alternatives. Tinosorb S and M (photostable, no benzophenone metabolite), Mexoryl SX and 400, mineral filters (zinc oxide, titanium dioxide).
Frequently asked questions
Is Octocrylene safe during pregnancy?
Octocrylene is not recommended during pregnancy. Consider an alternative from the same category.
What skin types is Octocrylene for?
Octocrylene suits: normal. Use with caution in: sensitive.
Can Octocrylene irritate the skin?
Octocrylene has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.
What is Octocrylene and what does it do in cosmetics?
UVB and partial UVA filter that stabilizes avobenzone in SPF formulas.
What's the INCI name for Octocrylene?
The INCI name is Octocrylene.
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