Padimate O
PABA derivative that moved from old sunscreens into niche cosmetics. Carries a notable allergy risk and shows phototoxicity.
Evidence by route
Topical application
Outdated UVB filter with a high contact-allergy rate. Modern ranges replace it with triazine filters.
How to read tiers A–F
- CWeak evidence. In vitro data, open-label studies, or expert consensus
Tolerability and safety
- Irritation potential
- Medium
- Allergen risk
- High
- Pregnancy
- Caution
- Use with caution
- Sensitive
About this ingredient
Padimate O (Ethylhexyl Dimethyl PABA) is an organic UVB filter, a para-aminobenzoic acid (PABA) derivative. Absorbs UV in the 290–320 nm range. Mechanism. The aminobenzoate chromophore absorbs UVB energy and dissipates it as heat. One of the first synthetic UV filters, developed in the 1940s. Since the 1990s partially displaced by newer filters over safety concerns. Where applied. Sunscreens in the US and Latin America. In the EU regulated under Regulation 1223/2009 – up to 8%, but used to a limited extent. In Spain rare in mass-market SPF formulas; avobenzone, octocrylene, octisalate are more common. Evidence base. SCCS confirmed safety up to 8%. FDA Cat I in the US. Safety. Contact allergies more frequent than with newer filters (1–2%). Cross-reaction in patients allergic to PABA, procaine, benzocaine. May leave yellow stains on white clothing. Pregnancy and lactation – manufacturers advise caution. No direct data. AAD 2023 recommends mineral filters (titanium dioxide, zinc oxide) in pregnancy.
Frequently asked questions
Is Padimate O safe during pregnancy?
Padimate O should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
What skin types is Padimate O for?
Use with caution in: sensitive.
Can Padimate O irritate the skin?
Padimate O has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.
Can Padimate O cause an allergic reaction?
Padimate O has high allergen potential. Perform a patch test on the inner forearm 24 hours before facial application.
What is Padimate O and what does it do in cosmetics?
PABA derivative that moved from old sunscreens into niche cosmetics.
What's the INCI name for Padimate O?
The INCI name is Ethylhexyl Dimethyl PABA. It may also appear as: Octyl Dimethyl PABA.
See Padimate O in a product composition right on the store page
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