Polyglutamic Acid
Biopolymer of gamma-glutamic acid produced by fermentation. Retains moisture 4–5 times more effectively than hyaluronic acid due to its large molecular network.
Moisturizing
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Small studies show superior hydration over hyaluronic acid with comparable tolerability. Inhibits hyaluronidase in vitro, potentially slowing degradation of the skin's own hyaluronic acid. Few independent RCTs.
- Ben-Zur N et al. J Cosmet Sci. 2007;58(4):381-394.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
DryNormalSensitiveCombinationOily
Frequently asked questions
Is Polyglutamic Acid safe during pregnancy?
Polyglutamic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Polyglutamic Acid for?
Polyglutamic Acid suits: dry, normal, sensitive, combination, oily.