Propylene Glycol

Dihydric alcohol that functions as a humectant and penetration enhancer. At high concentrations, it can irritate sensitive skin.

Moisturizing

Evidence by route

Topical application

Very weak or conflicting data.

Primary function is solvent and penetration enhancer. CIR deemed safe at concentrations up to 50%. Contact dermatitis reported in 1–3% of dermatology clinic patients on patch testing.

Lessmann H et al. Contact Dermatitis. 2005;53(3):150-156.

Tolerability and safety

Irritation potential

Medium

Allergen risk

Moderate

Pregnancy

Safe

For sensitive skin

Sensitive skin may experience irritation at concentrations above 10%. Causes contact allergy in 1–3% of individuals.

Skin types

Suitable for

NormalOilyCombination

Use with caution

SensitiveDry

Frequently asked questions

Is Propylene Glycol safe during pregnancy?

Propylene Glycol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Propylene Glycol for?

Propylene Glycol suits: normal, oily, combination. Use with caution in: sensitive, dry.

Can Propylene Glycol irritate the skin?

Propylene Glycol has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.