Tea Tree Oil
INCI: Melaleuca Alternifolia (Tea Tree) Leaf Oil
Essential oil with antibacterial activity against C. acnes. Terpinen-4-ol is the main active component. Acne efficacy confirmed, but irritation is possible.
Evidence by route
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
RCTs showed that 5% tea tree oil gel is slower than benzoyl peroxide but comparable in final efficacy for mild-to-moderate acne. Tolerability is better than benzoyl peroxide.
- Bassett IB et al. Med J Aust. 1990;153(8):455-458.
- Enshaieh S et al. Indian J Dermatol Venereol Leprol. 2007;73(1):22-25.
Working concentrations
5% in acne products
Tolerability and safety
Irritation potential
MediumAllergen risk
ModeratePregnancy
CautionFor sensitive skin
Oxidized tea tree oil is a potent sensitizer. Do not use old or improperly stored bottles.
Skin types
Suitable for
Use with caution
Frequently asked questions
Is Tea Tree Oil safe during pregnancy?
Tea Tree Oil should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
What skin types is Tea Tree Oil for?
Tea Tree Oil suits: oily, combination. Use with caution in: sensitive, dry.
Can Tea Tree Oil irritate the skin?
Tea Tree Oil has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.