Xylitylglucoside
Ester of xylitol and glucose. Humectant, component of Aquaxyl complex with confirmed hydration effect.
Evidence by route
Topical application
Safe humectant with accumulated evidence.
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Oily, Combination, Sensitive
About this ingredient
Xylitylglucoside is an ester of xylitol and glucose. A component of the Aquaxyl complex from Seppic (France) – one of the best-known cosmetic moisture-binding complexes. In Aquaxyl it combines with anhydroxylitol and xylitol for synergy. Mechanism. Humectant with extended hydration effect: beyond the classic moisture pull into the stratum corneum, it activates aquaporin-3 (AQP3) synthesis – water channels in keratinocyte membranes. Stimulates epidermal hyaluronic acid synthesis in vitro. Where applied. Moisturising serums and creams. In Spain – in Sesderma Hidraderm Hyal, Mesoestetic Hydra-Vital Factor K, ISDIN Hyaluronic Moisture lines. Aquaxyl complex in finished formulas – usually 3%, isolated xylitylglucoside – 0.5-2%. Evidence base. Seppic internal studies in 24 women over 28 days of 3% Aquaxyl use showed 25-30% hydration improvement and 15% TEWL reduction. Direct RCT comparisons with glycerin or hyaluronic acid have not been done. Safety. CIR has not evaluated it separately, but as a mixture of sugar esters it is safe. Non-sensitising, non-comedogenic. Pregnancy and lactation – safe. Usable without restrictions. Suited for. Dry, dehydrated skin, barrier recovery, anti-ageing prevention.
Frequently asked questions
Is Xylitylglucoside safe during pregnancy?
Xylitylglucoside is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Xylitylglucoside for?
Xylitylglucoside suits: normal, dry, oily, combination, sensitive.
What is Xylitylglucoside and what does it do in cosmetics?
Ester of xylitol and glucose.
What's the INCI name for Xylitylglucoside?
The INCI name is Xylitylglucoside.
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Xylose, Yogurt, Yogurt Powder, Zea Mays (Corn) Kernel Extract, Cetyl Ethylhexanoate, Glycoproteins, Laminaria Japonica Extract, Potassium Aspartate
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