ModerateAntiplatelet agents (low dose) / NSAIDs (analgesic dose)×Herbal agents for cognitive disorders
Updated · Methodology
Mechanism
The European monograph lists antiplatelet drugs alongside anticoagulants among treatments that raise bleeding risk with ginkgo. Aspirin blocks platelet cyclooxygenase irreversibly and ginkgo inhibits platelet-activating factor: two brakes on the same function at different points.
Symptoms
Easy bruising, prolonged bleeding from small wounds, nosebleeds. With antiplatelet-dose aspirin the gastrointestinal risk adds on, which ginkgo neither changes nor offsets.
Management
Declare ginkgo to whoever prescribes the aspirin. The monograph asks for consultation before use in patients on antiplatelets and for stopping it two weeks before surgery. If ginkgo is being taken for memory, weigh the fact that benefit in that indication is not established.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- EMA: European Union herbal monograph on Ginkgo biloba L., folium (2015)– EMA/HMPC, final EU herbal monograph, Ginkgo biloba L., folium