EEvigrade
RU

Ácido hialurónico

INCI: Sodium Hyaluronate

Polisacárido natural que fija agua hasta 1000 veces su propio peso. La aplicación tópica genera un efecto humectante superficial sin penetración en la dermis.

Moisturizing

Evidence by route

Topical application

C

Weak evidence. In vitro data, open-label studies, or expert consensus.

Surface humectant effect is well established. Data on dermal penetration and long-term wrinkle reduction remain conflicting: large HA molecules (>50 kDa) do not penetrate the stratum corneum. Low-molecular-weight fractions (<50 kDa) penetrate better but may cause irritation at high concentrations.

  • Papakonstantinou E et al. Dermatoendocrinol. 2012;4(3):253-258.

Injectable

A

Proven efficacy. Two or more independent RCTs with instrumental endpoints.

Cross-linked hyaluronic acid dermal fillers are the gold standard for contouring and biorevitalization. Multicenter clinical trials confirm efficacy and safety for wrinkle correction, volume restoration, and skin texture improvement.

  • Beasley KL et al. Dermatol Surg. 2009;35(Suppl 2):1642-1646.
  • Sundaram H et al. Plast Reconstr Surg. 2015;136(5 Suppl):139S-148S.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

OilyCombinationSensitiveNormalDry

Combinations with other ingredients

Works well with

CeramidesЦерамиды

Hyaluronic acid pulls water, ceramides hold it in the barrier. A baseline moisturizing combination.

NiacinamideНиацинамид

Safe pair for most routines. Niacinamide strengthens the barrier, hyaluronic acid retains water in the stratum corneum.

Frequently asked questions

¿Es seguro Ácido hialurónico durante el embarazo?

Ácido hialurónico se considera seguro durante el embarazo en concentraciones cosméticas habituales. La absorción sistémica a través de la piel es mínima.

¿Para qué tipos de piel sirve Ácido hialurónico?

Ácido hialurónico es adecuado para: grasa, mixta, sensible, normal, seca.